Propanoyl chloride, 3,3,3-trifluoro-2,2-dimethyl-
3,3,3-Trifluoro-2,2-dimethyl-propionyl chloride
CAS: 1163707-53-6
Molecular Formula: C5H6ClF3O
Propanoyl chloride, 3,3,3-trifluoro-2,2-dimethyl- - Names and Identifiers
Propanoyl chloride, 3,3,3-trifluoro-2,2-dimethyl- - Physico-chemical Properties
| Molecular Formula | C5H6ClF3O |
| Molar Mass | 174.55 |
| Density | 1.283±0.06 g/cm3(Predicted) |
| Boling Point | 94.0±35.0 °C(Predicted) |
Propanoyl chloride, 3,3,3-trifluoro-2,2-dimethyl- - Introduction
3,3, 3-Trifluoro-2, 2-dimethylpropionyl chloride is an organic compound with the chemical formula CF3COC(CH3)2Cl. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Density: 1.368g/cm³
-Boiling Point: 83-85°C
-Melting Point:-69°C
-Solubility: Soluble in organic solvents such as ether and alcohol, react with water to generate harmful gases
Use:
3,3, 3-Trifluoro-2, 2-dimethylpropionyl chloride is an important organic synthesis reagent, which is commonly used in chemical protection and substitution reactions in organic synthesis reactions. It can be used for the preparation of compounds with pharmacological and agro-pharmaceutical applications, such as glyphosate, triazuron, flurbiprofen and the like.
Method:
3,3, 3-Trifluoro-2, 2-dimethylpropanoyl chloride can be prepared by the following steps:
1. First, 2,2-dimethylpropionyl chloride is reacted with trifluoromethanesulfonic acid to generate 3,3, 3-trifluoro-2, 2-dimethylpropionyl trifluoromethanesulfonate.
2. The resulting triflate was then treated with sodium chloride to remove the triflate group to give 3,3, 3-trifluoro-2, 2-dimethylpropanoyl chloride.
Safety Information:
- 3,3, 3-Trifluoro-2, 2-dimethylpropionyl chloride is irritating and should be avoided in contact with the skin, eyes and respiratory system.
-When in use, should be carried out in a well-ventilated place, and wear appropriate protective equipment, such as chemical protective glasses, gloves and protective clothing.
-In case of accidental inhalation or contact, wash the affected area immediately and seek medical help.
-Waste disposal shall comply with local regulations and shall not be dumped.
Nature:
-Appearance: colorless liquid
-Density: 1.368g/cm³
-Boiling Point: 83-85°C
-Melting Point:-69°C
-Solubility: Soluble in organic solvents such as ether and alcohol, react with water to generate harmful gases
Use:
3,3, 3-Trifluoro-2, 2-dimethylpropionyl chloride is an important organic synthesis reagent, which is commonly used in chemical protection and substitution reactions in organic synthesis reactions. It can be used for the preparation of compounds with pharmacological and agro-pharmaceutical applications, such as glyphosate, triazuron, flurbiprofen and the like.
Method:
3,3, 3-Trifluoro-2, 2-dimethylpropanoyl chloride can be prepared by the following steps:
1. First, 2,2-dimethylpropionyl chloride is reacted with trifluoromethanesulfonic acid to generate 3,3, 3-trifluoro-2, 2-dimethylpropionyl trifluoromethanesulfonate.
2. The resulting triflate was then treated with sodium chloride to remove the triflate group to give 3,3, 3-trifluoro-2, 2-dimethylpropanoyl chloride.
Safety Information:
- 3,3, 3-Trifluoro-2, 2-dimethylpropionyl chloride is irritating and should be avoided in contact with the skin, eyes and respiratory system.
-When in use, should be carried out in a well-ventilated place, and wear appropriate protective equipment, such as chemical protective glasses, gloves and protective clothing.
-In case of accidental inhalation or contact, wash the affected area immediately and seek medical help.
-Waste disposal shall comply with local regulations and shall not be dumped.
Last Update：2024-04-10 22:29:15
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